Health Services Research (HSR) Methods
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Non-randomized Trial with Contemporaneous Controls
Synonyms: Simultaneous Nonrandomized controls

A type of trial in which treatment and control group participants are matched at the group level based on demographic and clinical characteristics, and receive different treatments (e.g. A and B) at the same time.

In these studies, outcomes are compared between the group receiving treatment A and the group receiving treatment B contemporaneously. Trials with contemporaneous controls are generally considered superior to a trial with historical controls.


Further Reading
Berger, M. et al. 2003. Health Care, Cost, Quality, and Outcomes: ISPOR Book of Terms, Lawrenceville, NJ: International Society for Pharmacoeconomics and Outcomes Research.